DNA Type 2 Diabetes Test
$349.00
Does diabetes run in your family?
Take this DNA test to understand your genetic risk for type 2 diabetes.
- Includes variants that influence glucose levels, fat metabolism, insulin production and response to insulin
- 70% chance of developing type 2 diabetes when both parents have the disease
- Private and confidential online results
- Painless sample collection
DESCRIPTION
Type 2 diabetes is a metabolic disorder that disrupts the body’s normal balance of glucose and insulin. It is typically linked to unhealthy lifestyles and excess body weight, but genetic variations can also raise the risk, regardless of lifestyle.
Glucose serves as the primary energy source for the cells in our bodies, and insulin, produced by the beta cells of the pancreas, regulates the levels of this simple sugar. Individuals with type 2 diabetes do not produce enough insulin, resulting in consistently elevated blood sugar levels.
A simple mouth swab can reveal whether you have inherited DNA changes that increase your risk of type 2 diabetes.
THE GENETICS
Genetic variations can affect our glucose and insulin levels, dietary fatty acid sensitivity, and insulin response, increasing the risk of developing type 2 diabetes. By understanding the genetic variants that increase the likelihood of developing this condition, you can make lifestyle changes to reduce your risk.
Tested Variants
| Gene(s) Tested | Effect |
| ACC2 | Reduced response to insulin |
| ADCY5 | Inhibited insulin secretion |
| FABP2, FTO | Increased absorption of saturated fats |
| ADIPOQ, CRY2, FADS1, G6PC2, GLUT2, MTNR1B, PROX1, TCF7L2 | Elevated fasting glucose levels |
| GCKR | Decreased fasting glucose levels |
| GCK, HNF4A | Reduced pancreatic beta cell function |
| GLIS3, IRS1, SLC30A8 | Disrupted insulin production, signaling, and storage |
| SHBG | Increased binding of sex hormones |
| MADD | Impaired conversion of proinsulin to insulin |
| SOD2 | Increased production of reactive oxygen species |
| HIF1A | Resistance to low oxygen levels |
DISCOVER MORE
How many risk factors for diabetes do you have?
- Genetic variations
- Family history of type 2 diabetes
- Obesity and abdominal fat accumulation
- Sedentary lifestyle and lack of physical activity
- Ethnicity, with African and Native American populations at higher risk
- Prediabetes, characterized by elevated blood sugar levels
- Gestational diabetes
- Polycystic ovarian syndrome
HOW IT WORKS
Step 1: Order test kit online
Step 2: Collect DNA sample using a painless mouth swab, and mail to the lab in the provided return envelope
Step 3: Receive your results online